Cotaus PCR Plates: Which Thermocycler Do They Fit?

If you’ve ever run a PCR and ended up with weird results, it might not be your primers or reagents—it could be your plate.

Yep, PCR plate and thermocycler compatibility is a big deal. If the plate doesn’t match the machine, you can lose heat efficiency, mess up sealing, or even risk contamination.

Here at Cotaus, we make PCR plates that play nicely with a wide range of thermocyclers, so you can just set up your experiment and hit “start” without worrying.

Why Compatibility Matters

  • Better Heat Transfer – A good fit means even heating across every well, which is key for accurate DNA amplification.

  • No Leaks or Evaporation – The right plate works perfectly with sealing films or caps.

  • Smooth Automation – Fully-skirted plates line up perfectly in robotic systems, avoiding costly errors.

Common Thermocycler Formats and Matching Plates

  • Standard 96-Well Plates – Works with most machines; available in skirted, semi-skirted, and non-skirted versions.

  • 384-Well Plates – For high-throughput runs; make sure your machine has a matching block.

  • Low-Profile Plates – Great for minimizing evaporation in long or hot protocols.

  • Fully-Skirted Plates – Rock solid in automated systems; also easy to handle manually.

  • Semi-Skirted / Non-Skirted – Good all-rounders, just check your block design before ordering.

Cotaus Compatibility Highlights

Our plates are made from medical-grade polypropylene and have tight tolerances, meaning they fit:

  • Applied Biosystems™ 7500, QuantStudio™ series

  • Bio-Rad® CFX96™, C1000 Touch™

  • Eppendorf® Mastercycler® series

  • Agilent® AriaMx

  • Thermo Fisher™ ProFlex™
    …and many more.

We’ve tested them for heat uniformity, sealing performance, and automation readiness.

Full Cotaus PCR Plates and Thermocycler Compatibility Table

Quick Tips for Choosing Your Plate

  1. Check your thermocycler’s block type (96-well, 384-well, low-profile).

  2. Pick the right skirt type for your workflow—full skirt for automation, non-skirt for budget-friendly manual runs.

  3. Use the right sealing option (optical film for qPCR, heat seal for storage).

Bottom line: With the right plate–machine combo, your PCR runs will be smoother, faster, and more reliable.
Browse the full Cotaus PCR plate range on our site and match them to your thermocycler today—your DNA will thank you.

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